LDN-27219 CHEMICAL STRUCTURE - AN OVERVIEW

LDN-27219 chemical structure - An Overview

Just one notably exciting compound is LDN-27219. Although most tTG inhibitors are made to bind to your protein crosslinking active site, LDN-27219 in its place binds on the nucleotide binding pocket in the enzyme while it can be in its shut-state conformation, and stabilizes that conformation to circumvent crosslinking activity.78 Schneider et al u

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